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Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development

Tipo de material: TextoTextoSeries ; Drug Discovery Today, 3(5), p.232-238, 1998Trabajos contenidos:
  • Verpoorte, R
Recursos en línea: Resumen: The drug discovery process increasingly requires the availability of large numbers of compounds. Chemodiversity in nature offers a valuable source; for example, secondary metabolites, previously regarded as waste products are now recognized for their resistant activity against pests and diseases. The author discusses some aspects of chemodiversity in plants and the role of secondary metabolites, and explains how exploitation of this resource might be helpful in the optimization of the lead discovery process.
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The drug discovery process increasingly requires the availability of large numbers of compounds. Chemodiversity in nature offers a valuable source; for example, secondary metabolites, previously regarded as waste products are now recognized for their resistant activity against pests and diseases. The author discusses some aspects of chemodiversity in plants and the role of secondary metabolites, and explains how exploitation of this resource might be helpful in the optimization of the lead discovery process.

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