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Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision

Tipo de material: TextoTextoSeries ; Genetics, 174, p.1397-1406, 2006Trabajos contenidos:
  • Fearnhead, P
Recursos en línea: Resumen: We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.
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We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.

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