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Fabrication and mechanical properties of PLA/HA composites: A study of in vitro degradation

Tipo de material: TextoTextoSeries ; Materials Science and Engineering, 26(8), p.1289-1295, 2006Trabajos contenidos:
  • J. Russias, E
  • Saiz, R.K
  • Nalla, K
  • Gryn, R.O
  • Ritchie, A.P. Tomsia
  • Saiz, R.K
  • Nalla, K
  • Nalla, K
  • Ritchie, A.P. Tomsia
Tema(s): Recursos en línea: Resumen: The adverse effects of stress shielding from the use of high-modulus metallic alloy bio-implant materials has led to increased research into developing polymer-ceramic composite materials that match the elastic modulus of human bone. Of particular interest are poly-l-lactic acid- hydroxyapatite (PLA/HA)-based composites which are fully resorbable in vivo. However, their bioresorbability has a deleterious effect on themechanical properties of the implant. The purpose of this study is to investigate, from a micromechanistic perspective, the in vitro degradation behavior of such composites manufactured using a simple hot-pressing route for two different hydroxyapatite particles
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The adverse effects of stress shielding from the use of high-modulus metallic alloy bio-implant materials has led to increased research into developing polymer-ceramic composite materials that match the elastic modulus of human bone. Of particular interest are poly-l-lactic acid- hydroxyapatite (PLA/HA)-based composites which are fully resorbable in vivo. However, their bioresorbability has a deleterious effect on themechanical properties of the implant. The purpose of this study is to investigate, from a micromechanistic perspective, the in vitro degradation behavior of such composites manufactured using a simple hot-pressing route for two different hydroxyapatite particles

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