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Isolation and structure elucidation of new phthalide and phthalane derivatives, isolated as antimicrobial agents from Emericella sp. IFM57991

Tipo de material: TextoTextoSeries ; Journal of Antibiotics, 69(2), p.89-96, 2016Trabajos contenidos:
  • Saito, T
  • Itabashi, T
  • Wakana, D
  • Takeda, H
  • Yaguchi, T
  • Kawai, K.-I
  • Hosoe, T
Tema(s): Recursos en línea: Resumen: Three new phthalide derivatives, emefuranones A1, A2 and B (1-3); six new phthalane derivatives, emefuran A, B1, B2, C1, C2 and D (4-9); three new farnesylated phthalide derivatives, farnesylemefuranones A-C (10-12); xylarinol C (13); and emericelloxide (14), along with four known compounds (dustanin, sorbicillin, aspergillodiol and xylarinol A), were isolated from the culture extracts of Emericella sp. IFM57991. Structures of 1-14 were elucidated on the basis of spectroscopic analysis and chemical evidence. Compounds 4-7 and 13 showed moderate antibacterial activities against Bacillus subtilis. © 2016 Japan Antibiotics Research Association.
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Documentos solicitados Documentos solicitados CICY Documento préstamo interbibliotecario Ref1 B-16491 (Browse shelf(Opens below)) Available

Three new phthalide derivatives, emefuranones A1, A2 and B (1-3); six new phthalane derivatives, emefuran A, B1, B2, C1, C2 and D (4-9); three new farnesylated phthalide derivatives, farnesylemefuranones A-C (10-12); xylarinol C (13); and emericelloxide (14), along with four known compounds (dustanin, sorbicillin, aspergillodiol and xylarinol A), were isolated from the culture extracts of Emericella sp. IFM57991. Structures of 1-14 were elucidated on the basis of spectroscopic analysis and chemical evidence. Compounds 4-7 and 13 showed moderate antibacterial activities against Bacillus subtilis. © 2016 Japan Antibiotics Research Association.

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