Fused deposition modeling of novel scaffold architectures for tissue engineering applications
Fused deposition modeling of novel scaffold architectures for tissue engineering applications
- BioMaterials, 23(4), p.1169-1185, 2002 .
Fused deposition modeling, a rapid prototyping technology, was used to produce novel scaffolds with honeycomb-like pattern, fully interconnected channel network, and controllable porosity and channel size. A bioresorbable polymer poly(e-caprolactone)(PCL)was developed as a filament modeling material to produce porous scaffolds, made of layers of directionally aligned microfilaments, using this computer-controlled extrusion and deposition process. The PCL scaffolds were produced with a range of channel size 160-700 mm, filament diameter 260-370 mm and porosity 48-77
TISSUE ENGINEERING
SCAFFOLD
FUSED DEPOSITION MODELING
BIORESORBABLE POLYMER
POROSITY
INTERCONNECTED CHANNEL NETWORK
COMPRESSIVE PROPERTIES
Fused deposition modeling, a rapid prototyping technology, was used to produce novel scaffolds with honeycomb-like pattern, fully interconnected channel network, and controllable porosity and channel size. A bioresorbable polymer poly(e-caprolactone)(PCL)was developed as a filament modeling material to produce porous scaffolds, made of layers of directionally aligned microfilaments, using this computer-controlled extrusion and deposition process. The PCL scaffolds were produced with a range of channel size 160-700 mm, filament diameter 260-370 mm and porosity 48-77
TISSUE ENGINEERING
SCAFFOLD
FUSED DEPOSITION MODELING
BIORESORBABLE POLYMER
POROSITY
INTERCONNECTED CHANNEL NETWORK
COMPRESSIVE PROPERTIES