The multitude of targets for the immune system and drug therapy in the fungal cell wall
The multitude of targets for the immune system and drug therapy in the fungal cell wall
- Microbes and Infection, 7, p.789-798, 2005 .
Recent studies on fungi revealed that several cytosolic and membrane components migrate to the cell wall together with secreted proteins and biosynthetic polysaccharides to build a dynamic immunoreactive structure. New aspects of fungal cell wall assembly and biosynthesis, focusing on the potential of glycolipids, melanin, heat-shock proteins, histone and surface antigens as targets of drugs and antifungal antibodies are discussed.
ANTIFUNGAL THERAPY
ANTIMICROBIAL ANTIBODIES
FUNGAL CELL WALL
UNFAMILIAR COMPONENTS
Recent studies on fungi revealed that several cytosolic and membrane components migrate to the cell wall together with secreted proteins and biosynthetic polysaccharides to build a dynamic immunoreactive structure. New aspects of fungal cell wall assembly and biosynthesis, focusing on the potential of glycolipids, melanin, heat-shock proteins, histone and surface antigens as targets of drugs and antifungal antibodies are discussed.
ANTIFUNGAL THERAPY
ANTIMICROBIAL ANTIBODIES
FUNGAL CELL WALL
UNFAMILIAR COMPONENTS