Membrane-bound geranylgeranyl diphosphate phosphatases: Purification and characterization from Croton stellatopilosus leaves

Membrane-bound geranylgeranyl diphosphate phosphatases: Purification and characterization from Croton stellatopilosus leaves - PhytoChemistry, 67(15), p.1613-1620, 2006 .

Geranylgeranyl diphosphate phosphatase is an enzyme catalyzing the dephosphorylation of geranylgeranyl diphosphate (GGPP)to form geranylgeraniol (GGOH). The enzyme activity of GGPP phosphatase was detected in leaves of Croton stellatopilosus, a Thai medicinal plant containing plaunotol, a commercial anti-peptic acyclic diterpenoid. Enzymological studies of GGPP phosphatase in C. stellatopilosis leaves revealed that the enzyme is a membrane-bound protein that could be removed from 20,000g pellet by 0.1


CROTON STELLATOPILOSUS
EUPHORBIACEAE
GERANYLGERANIOL
GERANYLGERANYL DIPHOSPHATE
GERANYLGERANYL DIPHOSPHATE PHOSPHATASE
ACYCLIC DITERPENE BIOSYNTHESIS
ENZYME PURIFICATION
ENZYME CHARACTERIZATION