Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 . broblasts in vitro
Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 . broblasts in vitro
- Journal of BioMaterials Science, Polymer Edition, 11, p.439-457, 2000 .
This work investigates the cytocompatibility of several photoinitiating systems for potential cell encapsulation applications. Both UV and visible light initiating schemes were examined. The UV photoinitiators included 2,2-dimethoxy-2-phenylacetophenone (Irgacure 651), 1-hydroxycyclohexyl phenyl ketone (Irgacure 184), 2-methyl-1-[4-(methylthio)phenyl]-2-(4-morpholinyl)- 1-propanone (Irgacure 907), and 2-hydroxy-1-[4-( hydroxyethoxy)phenyl]-2-methyl-1-propanone (Darocur 2959). The visible light initiating systems included camphorquinone (CQ)with ethyl 4-N,N-dimethylaminobenzoate (4EDMAB)and triethanolamine (TEA)and the photosensitizer isopropyl thioxanthone. A cultured . broblast cell line, NIH/3T3, was exposed to the photoinitiators at varying concentrations from 0.01
CYTOCOMPATIBILITY
PHOTOPOLYMERIZATION
TISSUE ENGINEERING
CELL ENCAPSULATION
PHOTOINITIATORS
This work investigates the cytocompatibility of several photoinitiating systems for potential cell encapsulation applications. Both UV and visible light initiating schemes were examined. The UV photoinitiators included 2,2-dimethoxy-2-phenylacetophenone (Irgacure 651), 1-hydroxycyclohexyl phenyl ketone (Irgacure 184), 2-methyl-1-[4-(methylthio)phenyl]-2-(4-morpholinyl)- 1-propanone (Irgacure 907), and 2-hydroxy-1-[4-( hydroxyethoxy)phenyl]-2-methyl-1-propanone (Darocur 2959). The visible light initiating systems included camphorquinone (CQ)with ethyl 4-N,N-dimethylaminobenzoate (4EDMAB)and triethanolamine (TEA)and the photosensitizer isopropyl thioxanthone. A cultured . broblast cell line, NIH/3T3, was exposed to the photoinitiators at varying concentrations from 0.01
CYTOCOMPATIBILITY
PHOTOPOLYMERIZATION
TISSUE ENGINEERING
CELL ENCAPSULATION
PHOTOINITIATORS