Applying systems and synthetic biology approaches to the production of food ingredients, enzymes and nutraceuticals by bacteria
Applying systems and synthetic biology approaches to the production of food ingredients, enzymes and nutraceuticals by bacteria
- Microbial Production of Food Ingredients, Enzymes and Nutraceuticals, p.81-96, 2013 .
Humans have exploited microorganisms for the production of foodstuffs and food additives for thousands of years. Empirical selection of strains for better or improved production has been a continuous process. Currently molecular biology, genetic engineering, genomics and systems biology are being exploited to speed up the process of selection in a rational fashion. In this chapter I discuss examples of how systems biology and related approaches have been used to inform the production of food-relevant ingredients. The chapter ends with a perspective on how systems biology will continue to develop and become more influential in this area of microbiology
CORYNEBACTERIUM
GENOME SCALE METABOLIC MAPS
METABOLIC ENGINEERING,
NEXT-GENERATION SEQUENCING
SYSTEMS BIOLOGY
Humans have exploited microorganisms for the production of foodstuffs and food additives for thousands of years. Empirical selection of strains for better or improved production has been a continuous process. Currently molecular biology, genetic engineering, genomics and systems biology are being exploited to speed up the process of selection in a rational fashion. In this chapter I discuss examples of how systems biology and related approaches have been used to inform the production of food-relevant ingredients. The chapter ends with a perspective on how systems biology will continue to develop and become more influential in this area of microbiology
CORYNEBACTERIUM
GENOME SCALE METABOLIC MAPS
METABOLIC ENGINEERING,
NEXT-GENERATION SEQUENCING
SYSTEMS BIOLOGY