Poly(ADP-Ribosyl)ation

Bürkle, Alexander.

Poly(ADP-Ribosyl)ation [recurso electrónico] / by Alexander Bürkle. - XVII, 246 p. online resource. - Molecular Biology Intelligence Unit . - Molecular Biology Intelligence Unit .

Enzymes in Poly(ADP-Ribose) Metabolism -- PARP-2: Structure-Function Relationship -- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals -- DNA Damage Signaling through Poly(ADP-Ribose) -- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity -- Functional Interactions of PARP-1 with p53 -- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1 -- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders -- PARP and Epigenetic Regulation -- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria -- Genome Degradation by DNAS1L3 Endonuclease -- NAD: Metabolism and Regulatory Functions -- PARP-1 and the Shape of Cell Death -- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity -- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury -- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock -- Role of Poly-ADP-Ribosylation in Cancer Development -- PARP Inhibitors and Cancer Therapy -- Poly(ADP-Ribosyl)ation and Aging.

Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter.

9780387360058 99780387360058

10.1007/0-387-36005-0 doi


MEDICINE.
HUMAN GENETICS.
MICROBIOLOGY.
BIOCHEMISTRY.
CYTOLOGY.
BIOMEDICINE.
MEDICAL MICROBIOLOGY.
HUMAN GENETICS.
BIOCHEMISTRY, GENERAL.
CELL BIOLOGY.

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