Large-Scale Comparison of Fungal Sequence Information: Mechanisms of Innovation in Neurispora crassa and Gene Loss in Sccharomyces cerevisiae (Record no. 39308)
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| fixed length control field | 02098nam a2200205Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625122449.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-4949 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Large-Scale Comparison of Fungal Sequence Information: Mechanisms of Innovation in Neurispora crassa and Gene Loss in Sccharomyces cerevisiae |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Genome Research, 10, p.416-430, 2000 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | We report a large-scale comparison of sequence data from the filamentous fungus Neurospora crassa with the complete genome sequence of Saccharomyces cerevisiae. N. crassa is considerably more morphologically and developmentally complex than S. cerevisiae. We found that N. crassa has a much higher proportion of "orphan" genes than S. cerevisiae, suggesting that its morphological complexity reflects the acquisition or maintenance of novel genes, consistent with its larger genome. Our results also indicate the loss of specific genes from S. cerevisiae. Surprisingly, some of the genes lost from S. cerevisiae are involved in basic cellular processes, including translation and ion (especially calcium)homeostasis. Horizontal gene transfer from prokaryotes appears to have played a relatively modest role in the evolution of the N. crassa genome. Differences in the overall rate of molecular evolution between N. crassa and S. cerevisiae were not detected. Our results indicate that the current public sequence databases have fairly complete samples of gene families with ancient conserved regions, suggesting that further sequencing will not substantially change the proportion of genes with homologs among distantly related groups. Models of the evolution of fungal genomes compatible with these results, and their functional implications, are discussed. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Braun, E.L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Halper, A.L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nelson, M.A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Natvig, D.O. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1U6FcxqJxFEyPLlQ8h_DqfCu6mV1d5GA8/view?usp=drivesdk">https://drive.google.com/file/d/1U6FcxqJxFEyPLlQ8h_DqfCu6mV1d5GA8/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-4949 | 25.06.2025 | 25.06.2025 | Documentos solicitados |