Asymmetrically acting lycopene -cyclases (CrtLm)from non-photosynthetic bacteria (Record no. 40342)
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| fixed length control field | 02089nam a2200253Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625122509.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-5997 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Asymmetrically acting lycopene -cyclases (CrtLm)from non-photosynthetic bacteria |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Molecular Genetics and Genomics , 271(2), p. 180-188, 2004 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Carotenoids have important functions in photosynthesis, nutrition, and protection against oxidative damage. Some natural carotenoids are asymmetrical molecules that are difficult to produce chemically. Biological production of carotenoids using specific enzymes is a potential alternative to extraction from natural sources. Here we report the isolation of lycopene -cyclases that selectively cyclize only one end of lycopene or neurosporene. The crtLm genes encoding the asymmetrically acting lycopene -cyclases were isolated from non-photosynthetic bacteria that produced monocyclic carotenoids. Co-expression of these crtLm genes with the crtEIB genes from Pantoea stewartii (responsible for lycopene synthesis)resulted in the production of monocyclic -carotene in Escherichia coli. The asymmetric cyclization activity of CrtLm could be inhibited by the lycopene -cyclase inhibitor 2-(4-chlorophenylthio)-triethylamine (CPTA). Phylogenetic analysis suggested that bacterial CrtL-type lycopene -cyclases might represent an evolutionary link between the common bacterial CrtY-type of lycopene -cyclases and plant lycopene - and -cyclases. These lycopene -cyclases may be used for efficient production of high-value asymmetrically cyclized carotenoids. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CAROTENOIDS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | LYCOPENE CYCLASE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ASYMMETRIC CYCLIZATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MONOCYCLIC CAROTENOIDS |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tao, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Picataggio, S |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rouvière, P.E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cheng, Q. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/18F5IR1FIOvjicZH_fO1vpnVaB7aopgzF/view?usp=drivesdk">https://drive.google.com/file/d/18F5IR1FIOvjicZH_fO1vpnVaB7aopgzF/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-5997 | 25.06.2025 | 25.06.2025 | Documentos solicitados |