MAPK-regulated transcription: a continuously variable gene switch? (Record no. 40379)

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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6034
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Title MAPK-regulated transcription: a continuously variable gene switch?
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Volume/sequential designation Nature Reviews Molecular Cell Biology , 3(1), p.30-40, 2001
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Summary, etc. Switching mechanisms that control genes could be viewed either as stable binary switches, in which genes exist in 'on' or 'off' states; or as quantitative rheostat-like switches, in which the rate of transcription is continuously variable and coupled directly to the strength of intracellular signalling events. Here, we discuss the biological need for quantitative gene regulation and, using mitogen-activated protein kinase (MAPK)-controlled transcription as a model, assess the evidence for its existence and postulate mechanisms by which it might occur.
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Personal name Hazzalin, C.A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mahadevan, L.C.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/157tkoynC5l9jfWk5F0xa2o1cLpXxmaVz/view?usp=drivesdk">https://drive.google.com/file/d/157tkoynC5l9jfWk5F0xa2o1cLpXxmaVz/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-6034 25.06.2025 25.06.2025 Documentos solicitados