Gene disruption to evaluate the role of fungal candidate virulence genes (Record no. 40503)

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control field 20250625124637.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6158
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245 10 - TITLE STATEMENT
Title Gene disruption to evaluate the role of fungal candidate virulence genes
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Volume/sequential designation Current Opinion in MicroBiology, 1(4), p.381-389, 1998
520 3# - SUMMARY, ETC.
Summary, etc. Gene disruption is a powerful genetic tool that can define pathogenic or virulence factors. In the past two years gene disruption approaches have been used to identify fungal virulence genes. The capsule genes, an subunit of G protein and certain kinases of Cryptococcus neoformans have clearly been demonstrated to be associated with pathogenicity. In Candida albicans at least four genes involved in hyphal formation have been disrupted and tested for virulence. In other fungi, such as Histoplasma capsulatum, however, more efficient gene disruption methods need to be developed before such approaches can be regularly used for identifying virulence genes.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kwon-Chung, K.J.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1p3wqMNFLE-qPu-2QRSo3ODcMSkqWUKnZ/view?usp=drivesdk">https://drive.google.com/file/d/1p3wqMNFLE-qPu-2QRSo3ODcMSkqWUKnZ/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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