A novel `two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans (Record no. 40512)

MARC details
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fixed length control field 01565nam a2200229Ia 4500
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625124638.0
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Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6167
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Title A novel `two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans
490 0# - SERIES STATEMENT
Volume/sequential designation Current Genetics, 37(6), p.364 - 372, 2000
520 3# - SUMMARY, ETC.
Summary, etc. Abstract We have characterised a novel Aspergillus nidulans gene encoding a `two-component' signalling protein (tcsA). tcsA encodes both a histidine kinase domain and a response regulator domain similar to those found in bacterial, lower eukaryotic and plant members of the two-component family of proteins, while two PAS domains in the amino-terminal region of the predicted tcsA product may monitor the signal which regulates a tcsA histidine kinase-response regulator phosphorelay. While tcsA is nonessential for vegetative growth, cells lacking the gene are unable to produce conidia on standard Aspergillus growth media. However, tcsA is not absolutely required for production since this defect is suppressed by growth on 1 M sorbitol.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ASPERGILLUS NIDULANS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TCSA GENE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TWO-COMPONENT SYSTEM
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Appleyard, M.V.C.L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name McPheat, W.L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Stark, M.J.R.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1lS9HL9aq5WWIvBthNP3JSfDEadQtWJc7/view?usp=drivesdk">https://drive.google.com/file/d/1lS9HL9aq5WWIvBthNP3JSfDEadQtWJc7/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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