MARC details
| 000 -LEADER |
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| fixed length control field |
01813nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625124642.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-6394 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Evaluation of African medicinal plants for their in vitro trypanocidal activity |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Journal of EthnoPharmacology, 55(1), p.1-11, 1996 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Petroleum ether, dichloromethane, methanol and water extracts from 24 plants, belonging to 19 families, which are reported in the literature as traditional remedies for sleeping sickness (human African trypanosomiasis)were screened for in vitro activity against Trypanosoma brucei rhodesiense, as well as for cytotoxicity for a human fibroblast cell-line (WI-38). The trypanocidal activity of the natural compounds berberine and harmane, both documented as being trypanocidal, was also evaluated. Promising trypanocidal activity with IC50 values below 10 g/ml was found in 32 extracts of 13 plant species. The most active extracts with IC50 values below 1 g/ml were derived from Annona senegalensis, Bussea occidentalis and Physalis angulata. The plant extracts showed a modest selectivity index, in contrast to commercially available trypanocides which have a more distinct selective toxicity against trypanosomes. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MEDICINAL PLANTS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SLEEPING SICKNESS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
TRYPANOSOMA BRUCEI RHODESIENSE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTITRYPANOSOMAL ACTIVITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN VITRO |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
AFRICA |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Freiburghaus, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kaminsky, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Nkunya, M.H.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Brun, R. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/16S4M57c29Hbws0DhviVNtN4dhi4rjtnD/view?usp=drivesdk">https://drive.google.com/file/d/16S4M57c29Hbws0DhviVNtN4dhi4rjtnD/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
