Synteny in Toxigenic Fusarium Species: The Fumonisin Gene Cluster and the Mating Type Region as Examples (Record no. 40785)

MARC details
000 -LEADER
fixed length control field 02567nam a2200277Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625124643.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6441
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245 10 - TITLE STATEMENT
Title Synteny in Toxigenic Fusarium Species: The Fumonisin Gene Cluster and the Mating Type Region as Examples
490 0# - SERIES STATEMENT
Volume/sequential designation European Journal of Plant Pathology, 110(5-6), p.533-544, 2004
520 3# - SUMMARY, ETC.
Summary, etc. A comparative genomic approach was used to study the mating type locus and the gene cluster involved in toxin production (fumonisin)in Fusarium proliferatum, a pathogen with a wide host range and a complex toxin profile. A BAC library, generated from F. proliferatum isolate ITEM 2287, was used to identify chromosomal regions flanking the mating type locus and the gene cluster involved in the biosynthesis of fumonisin. These regions were sequenced and compared with corresponding sequences in other ascomycetes. The results demonstrated that the level of synteny between ascomycetes can vary greatly for different genomic regions and that the level of similarity of genes within a region can also fluctuate strongly. Synteny was found in the regions flanking the mating type idiomorph among ascomycetes that supposedly diverged 280 million years ago. The fumonisin gene clusters of F. proliferatum and F. verticillioides were completely syntenic but absent in F. graminearum. The regions flanking the fumonisin gene clusters were highly dissimilar between F. proliferatum and F. verticillioides, whereas they formed a continuous region in F. graminearum. This indicates that the fumonisin gene cluster has been inserted at different genome locations in both species. Surprisingly low similarity was found between the corresponding genes within the fumonisin cluster of F. proliferatum and F. verticillioides, compared to other genomic sequences indicative for two independent acquisition events from distinct genetic sources. The results demonstrate the power of comparative genomics for gene annotation and for studies on the evolution of genes, gene-clusters and species.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GENOME
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GIBBERELLA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PLANT PATHOGEN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TOXIN
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Waalwijk, C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name van der Lee, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name de Vries, I.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hesselink, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Arts, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kema, G.H.J.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1u4AhcXCtzX2fvtBg3GQ8G5KMQR9MsGuY/view?usp=drivesdk">https://drive.google.com/file/d/1u4AhcXCtzX2fvtBg3GQ8G5KMQR9MsGuY/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-6441 25.06.2025 25.06.2025 Documentos solicitados