The origin of genetic information: viruses as models (Record no. 41184)

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fixed length control field 01751nam a2200265Ia 4500
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control field MX-MdCICY
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control field 20250625124650.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6846
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Title The origin of genetic information: viruses as models
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Volume/sequential designation Gene , 135(1-2), p.37-47, 1993
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Summary, etc. living entity can be described as a complex adaptive system which differs from any, however complex, chemical structure by its capability of functional self-organization based on the processing of information. If one asks, where does this information come from and what is its primary semantics, the answer is: information generates itself in feedback loops via replication and selection, the objective being 'to be or not to be'. This paper describes the theoretical framework of information-generating systems and provides experimental clues for some basic forms of genetic organization, such as molecular quasi-species, hypercyclic and compartmentalized RNA-protein assemblies. The results are primarily obtained with RNA viruses and virus-like systems. The experiments are carried out with the help of automated, computer-controlled bioreactors, called 'evolution machines', that may form the basis of a new 'evolutionary biotechnology'.
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Topical term or geographic name entry element MOLECULAR EVOLUTION
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Topical term or geographic name entry element SEQUENCE SPACE
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Topical term or geographic name entry element ERROR THRESHOLD
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Topical term or geographic name entry element SELECTION
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Topical term or geographic name entry element QUASI-SPECIES
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Topical term or geographic name entry element RNA VIRUSES
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Topical term or geographic name entry element HYPERCYCLES
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Topical term or geographic name entry element EVOLUTIONARY BIOTECHNOLOGY
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Personal name Eigen, M.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Ubml1kuamgHvHe49V4icPGM1onr-AIm8/view?usp=drivesdk">https://drive.google.com/file/d/1Ubml1kuamgHvHe49V4icPGM1onr-AIm8/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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