Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains (Record no. 41201)

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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6863
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Title Comparative genome hybridization reveals widespread aneuploidy in Candida albicans laboratory strains
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Volume/sequential designation Molecular MicroBiology, 55(5), p.1553-1565, 2005
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Summary, etc. Clinical strains of Candida albicans are highly tolerant of aneuploidies and other genome rearrangements. We have used comparative genome hybridization (CGH), in an array format, to analyse the copy number of over 6000 open reading frames (ORFs)in the genomic DNA of C. albicans laboratory strains carrying one (CAI-4)to three (BWP17)auxotrophies. We find that during disruption of the HIS1 locus all genes telomeric to HIS1 were deleted and telomeric repeats were added to a 9 nt sequence within the transforming DNA. This deletion occurred in ~ 10
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Personal name Selmecki, A.
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Personal name Bergmann, S.
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Personal name Berman, J.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1oSqNRvKF22ya9499aHcAUhMMB38o4qOf/view?usp=drivesdk">https://drive.google.com/file/d/1oSqNRvKF22ya9499aHcAUhMMB38o4qOf/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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