The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. (Record no. 41228)

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control field MX-MdCICY
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control field 20250625124651.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-6891
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Title The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans.
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Volume/sequential designation Science, 307(5713), p.1321-1324, 2005
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Summary, etc. Cryptococcus neoformans is a basidiomycetous yeast ubiquitous in the environment, a model for fungal pathogenesis, and an opportunistic human pathogen of global importance. We have sequenced its approximately 20-megabase genome, which contains approximately 6500 intron-rich gene structures and encodes a transcriptome abundant in alternatively spliced and antisense messages. The genome is rich in transposons, many of which cluster at candidate centromeric regions. The presence of these transposons may drive karyotype instability and phenotypic variation. C. neoformans encodes unique genes that may contribute to its unusual virulence properties, and comparison of two phenotypically distinct strains reveals variation in gene content in addition to sequence polymorphisms between the genomes.
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Personal name Loftus, B.J.
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Personal name Fung. E.
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Personal name Roncaglia, P.
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Personal name Rowley, D.
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Personal name Amedeo, P.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Tye1_T8UFAqjg6NMfSfFay3UfhopcBfd/view?usp=drivesdk">https://drive.google.com/file/d/1Tye1_T8UFAqjg6NMfSfFay3UfhopcBfd/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-6891 25.06.2025 25.06.2025 Documentos solicitados