Distribution of the vanilloid (capsaicin)receptor type 1 in the human stomach (Record no. 41414)
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| fixed length control field | 02400nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625124654.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-7081 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Distribution of the vanilloid (capsaicin)receptor type 1 in the human stomach |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | HistoChemistry and Cell Biology, 2005 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Abstract Vanilloid receptor type 1 (TRPV1)is expressed in a capsaicin-sensitive and peptide-containing subpopulation of primary sensory nerves that in the rat stomach seems involved in regulation of chlorhydropeptic secretion and gastroprotection. Our aim was to identify which cell types express TRPV1 in the human stomach in order to gain a better insight in the role of this receptor in the regulation of HCl secretion. Immunohistochemistry, by using three different commercially available anti-capsaicin antibodies, in situ hybridisation and Western blot analysis were performed on fragments surgically obtained from the gastric body on the large curvature. TRPV1 labelling was found in the parietal cells at the level of intra-cytoplasmatic granules matching mitochondrial features and istribution. Immunolabelled neurons and nerve fibres were also seen, the latter numerous in the submucosa and mucosa and often ending close to the parietal cells. TRPV1 presence was confirmed by Western blot analysis and in situ hybridisation. TRPV1 presence in nerve structures and parietal cells suggests the possibility of a combined effect of both neuronal and epithelial TRPV1 on Chlorhydropeptic secretion. The presumed TRPV1 mitochondrial location inside parietal cells is in favour of the existence of a local pathway of auto-regulation of HCl secretion. Therefore, TRPV1 might modulate chlorhydropeptic secretion in the human stomach through more complex pathways than previously thought. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | VANILLOID RECEPTOR |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | IMMUNOHISTOCHEMISTRY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PARIETAL CELLS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SENSORY INNERVATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HUMAN STOMACH |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faussone-Pellegrini, Ms |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Taddei, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bizzoco, E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lazzeri, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vannucchi, M.G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bechi, P. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1sHYr7iGCw49MfBmbPAf3QXEhq0sfBRti/view?usp=drivesdk">https://drive.google.com/file/d/1sHYr7iGCw49MfBmbPAf3QXEhq0sfBRti/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-7081 | 25.06.2025 | 25.06.2025 | Documentos solicitados |