MARC details
| 000 -LEADER |
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02265nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625124657.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-7258 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Specific molecular features in the organization and biosynthesis of the cell wall of Aspergillus fumigatus |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Medical Mycology Supplement, 43(1 S), p.15-22, 2005 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
The cell wall of Aspergillus fumigatus is composed of a branched b1,3 glucan covalently bound to chitin, b1,3, b1,4 glucans, and galactomannan, that is embedded in an amorphous cement composed of a1,3 glucan, alactomannan and polygalactosamin. The mycelial cell wall of A. fumigatus is very different from the yeast Saccharomyces cerevisiae cell wall, and in particular lacks b1,6 glucans and proteins covalently bound to cell wall polysaccharides. The differences in cell wall composition between the mould A. fumigatus and the yeast S. cerevisiae are also reflected at the genomic level where unique features have been identified in A. fumigatus. A single gene codes for the glucan synthase catalytic subumit; this finding has lead to the development of a RNAi methodology for the disruption of essential genes in A. fumigatus. In contrast to the glucan synthase, multiple genes have been found in the chitin synthase and the alpha glucan synthase families; in spite of homologous sequences, each gene in each family have very different function. Similarly homologous mannosyltransferase genes are found in yeast and moulds but they lead to the synthesis of very different N-mannan structures. This chemo-genomic comparative analysis has also suggested that GPI-anchored proteins do not have a role of linker in the three dimensional organization of the fungal cell wall. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CELL WALL |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GLUCAN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CHITIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MANNAN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GPI |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Latge, J.P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mouyna, I. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Tekaia, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Beauvais, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Debeaupuis, J.P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Nierman, W. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1ZoDnnkp0dWkyINZX3BnJz2Umf821ml7O/view?usp=drivesdk">https://drive.google.com/file/d/1ZoDnnkp0dWkyINZX3BnJz2Umf821ml7O/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
