Biodegradable Polymer Scaffolds with Well-Defined Interconnected Spherical Pore Network (Record no. 41625)

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control field MX-MdCICY
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control field 20250625124658.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7294
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245 10 - TITLE STATEMENT
Title Biodegradable Polymer Scaffolds with Well-Defined Interconnected Spherical Pore Network
490 0# - SERIES STATEMENT
Volume/sequential designation Tissue Engineering, 7, p.23-33, 2001
520 3# - SUMMARY, ETC.
Summary, etc. Scaffolding plays pivotal role in tissue engineering. In this work, a novel processing technique has been developed to create three-dimensional biodegradable polymer scaffolds with well-controlled interconnected spherical pores. Paraffin spheres were fabricated with a dispersion method, and were bonded together through a heat treatment to form a three-dimensional assembly in a mold. Biodegradable polymers such as PLLA and PLGA were dissolved in a solvent and cast onto the paraffin sphere assembly. After dissolving the paraffin, a porous polymer scaffold was formed. The fabrication parameters were studied in relation to the pore shape, interpore connectivity, pore wall morphology, and mechanical properties of the polymer scaffolds. The compressive modulus of the scaffolds decreased with increasing porosity. Longer heat treatment time of the paraffin spheres resulted in larger openings between the pores of the scaffolds. Foams of smaller pore size (100-200 mm)resulted in significantly lower compressive modulus than that of larger pore sizes (250-350 or 420-500 mm). The PLLA foams had a skeletal structure consisting of small platelets, whereas PLGA foams had homogeneous skeletal structure. The new processing technique can tailor the polymer scaffolds for a variety of potential tissue engineering applications because of the wellcontrolled architecture, interpore connectivity, and mechanical properties.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ma, P.X.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Choi, J.W.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1B4L8xOwvRwdULRQZ_GzjhlPeUcXqdG1R/view?usp=drivesdk">https://drive.google.com/file/d/1B4L8xOwvRwdULRQZ_GzjhlPeUcXqdG1R/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7294 25.06.2025 25.06.2025 Documentos solicitados