Twists, Knots, and Rings in Proteins STRUCTURAL DEFINITION OF THE CYCLOTIDE FRAMEWORK (Record no. 41709)
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| fixed length control field | 01674nam a2200217Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625124700.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-7378 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Twists, Knots, and Rings in Proteins STRUCTURAL DEFINITION OF THE CYCLOTIDE FRAMEWORK |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | The Journal of Biological Chemistry, 278(10), p.8606-8616, 2003 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | In recent years an increasing number of miniproteins containing an amide-cyclized backbone have been discovered. The cyclotide family is the largest group of such proteins and is characterized by a circular protein backbone and six conserved cysteine residues linked by disulfide bonds in a tight core of the molecule. These form a cystine knot in which an embedded ring formed by two of the disulfide bonds and the connecting backbone segment is threaded by a third disulfide bond. In the current study we have undertaken high resolution structural analysis of two prototypic cyclotides, kalata B1 and cycloviolacin O1, to define the role of the conserved residues in the sequence. We provide the first comprehensive analysis of the topological features in this unique family of proteins, namely rings (a circular backbone), twists (a cis-peptide bond in the Mo¨ bius cyclotides)and knots (a knotted arrangement of the disulfide bonds). |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rosengren, K.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Daly, N.L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Plan, M.R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Waine, C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Craik, D.J. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1UlHdBuzNbx8oizVcU4l0j1EUBfgl-AVj/view?usp=drivesdk">https://drive.google.com/file/d/1UlHdBuzNbx8oizVcU4l0j1EUBfgl-AVj/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-7378 | 25.06.2025 | 25.06.2025 | Documentos solicitados |