MARC details
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02190nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20250625124702.0 |
| 040 ## - CATALOGING SOURCE |
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CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-7502 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
An introduction to TRP channels |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Annu. Rev. Physiol., 68, p.619-647, 2006 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
The aim of this reviewis to provide a basic framework for understanding the function of mammalian transient receptor potential (TRP)channels, particularly as they have been elucidated in heterologous expression systems. Mammalian TRP channel proteins form six-transmembrane (6-TM)cation-permeable channels that may be grouped into six subfamilies on the basis of amino acid sequence homology (TRPC, TRPV, TRPM, TRPA, TRPP, and TRPML). Selected functional properties of TRP channels from each subfamily are summarized in this review. Although a single defining characteristic of TRP channel function has not yet emerged, TRP channels may be generally described as calcium-permeable cation channels with polymodal activation properties. By integrating multiple concomitant stimuli and coupling their activity to downstream cellular signal amplification via calcium permeation and membrane depolarization, TRP channels appear well adapted to function in cellular sensation. Our review of recent literature implicating TRP channels in neuronal growth cone steering suggests that TRPs may function more widely in cellular guidance and chemotaxis. The TRP channel gene family and its nomenclature, the encoded proteins and alternatively spliced variants, and the rapidly expanding pharmacology of TRP channels are summarized in online supplemental material. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
TRANSIENT RECEPTOR POTENTIAL |
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CALCIUM PERMEABLE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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VOLTAGE DEPENDENT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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LIGAND GATED |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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AXON GUIDANCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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PHARMACOLOGY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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SPLICE VARIANTS |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ramsey, I.S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Delling, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Clapham, D.E. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/14mE1RCvxNMGniM1D_VH87x-xbnqz8nZD/view?usp=drivesdk">https://drive.google.com/file/d/14mE1RCvxNMGniM1D_VH87x-xbnqz8nZD/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
