Rewiring Mitogen-Activated Protein Kinase Cascade by Positive Feedback Confers Potato Blight Resistance1 (Record no. 41932)

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control field MX-MdCICY
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control field 20250625124704.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7608
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Title Rewiring Mitogen-Activated Protein Kinase Cascade by Positive Feedback Confers Potato Blight Resistance1
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Volume/sequential designation Plant Physiology, 140(2), p.681-692, 2006
520 3# - SUMMARY, ETC.
Summary, etc. Late blight, caused by the notorious pathogen Phytophthora infestans, is a devastating disease of potato (Solanum tuberosum)and tomato (Solanum lycopersicum), and during the 1840s caused the Irish potato famine and over one million fatalities. Currently, grown potato cultivars lack adequate blight tolerance. Earlier cultivars bred for resistance used disease resistance genes that confer immunity only to some strains of the pathogen harboring corresponding avirulence gene. Specific resistance genemediated immunity and chemical controls are rapidly overcome in the field when new pathogen races arise through mutation, recombination, or migration from elsewhere. A mitogen-activated protein kinase (MAPK)cascade plays a pivotal role in plant innate immunity. Here we show that the transgenic potato plants that carry a constitutively active form of MAPK kinase driven by a pathogen-inducible promoter of potato showed high resistance to early blight pathogen Alternaria solani as well as P. infestans. The pathogen attack provoked defense-related MAPK activation followed by induction of NADPH oxidase gene expression, which is implicated in reactive oxygen species production, and resulted in hypersensitive response-like phenotype. We propose that enhancing disease resistance through altered regulation of plant defense mechanisms should be more durable and publicly acceptable than engineering overexpression of antimicrobial proteins.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yamamizo, Ch.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kuchimura, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kobayashi, A.
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Personal name Katou, S.
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Personal name Kawakita, K.
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Personal name Jones, J.D.G.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Doke, N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Doke, N.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1IOC8oStVmn55c1gxlvv2ARjI9gQrEW7I/view?usp=drivesdk">https://drive.google.com/file/d/1IOC8oStVmn55c1gxlvv2ARjI9gQrEW7I/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7608 25.06.2025 25.06.2025 Documentos solicitados