Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response (Record no. 41953)

MARC details
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fixed length control field 01714nam a2200229Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625124704.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7629
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Title Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
490 0# - SERIES STATEMENT
Volume/sequential designation Cell, 121(4), p.567-577, 2005
520 3# - SUMMARY, ETC.
Summary, etc. The plant innate immune response includes the hypersensitive response (HR), a form of programmed cell death (PCD). PCD must be restricted to infection sites to prevent the HR from playing a pathologic rather than protective role. Here we show that plant BECLIN 1, an ortholog of the yeast and mammalian autophagy gene ATG6/VPS30/beclin 1, functions to restrict HR PCD to infection sites. Initiation of HR PCD is normal in BECLIN 1-deficient plants, but remarkably, healthy uninfected tissue adjacent to HR lesions and leaves distal to the inoculated leaf undergo unrestricted PCD. In the HR PCD response, autophagy is induced in both pathogen-infected cells and distal uninfected cells; this is reduced in BECLIN 1-deficient plants. The restriction of HR PCD also requires orthologs of other autophagy-related genes including PI3K/VPS34, ATG3, and ATG7. Thus, the evolutionarily conserved autophagy pathway plays an essential role in plant innate immunity and negatively regulates PCD.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Liu, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Schiff, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Czymmek, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tallóczy, Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Levine, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Dinesh-Kumar, S.P.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1WJQkgvKQCTTOyEPgMWb6ks7oksZFXhYK/view?usp=drivesdk">https://drive.google.com/file/d/1WJQkgvKQCTTOyEPgMWb6ks7oksZFXhYK/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7629 25.06.2025 25.06.2025 Documentos solicitados