Toxicological Effects of Alfa-Solamargine in Experimental Animals (Record no. 42146)

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003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625124708.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7833
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245 10 - TITLE STATEMENT
Title Toxicological Effects of Alfa-Solamargine in Experimental Animals
490 0# - SERIES STATEMENT
Volume/sequential designation Phytotherapy Research, 17(3), p.254-258, 2003
520 3# - SUMMARY, ETC.
Summary, etc. Alfa-Solamargine isolated from the fresh fruits of Solanum americanum Miller was studied for its toxicity. Lethality studies in rats showed a dose-mortality relationship with a LD50 of 42 mg/kg body weight intraperitoneally. The chronic and subchronic toxicity investigations indicated that the size of the glycoalkaloid dose was more important than the total glycoalkaloid intake. No appreciable toxic effects were observed at doses below 35 mg/kg body weight as indicated by blood parameters, enzyme levels and histological sections of kidney, liver and cardiac muscle. á-Solamargine did not affect the weight of the testes and epididymis or the number of spermatozoa but produced a slight irritation and congestion in the epididymis and testis at doses up to 50 mg/kg body weight.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SOLAMARGINE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SOLANACEAE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GLYCOALKALOIDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TOXICOLOGY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHARMACOLOGY
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chami, L.A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Méndez, B
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chataing, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name O'Callaghan, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Usubillaga, A
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name LaCruz, L.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Vb2yxmzRfhqiaPi5h7XxHEdgZPLJl9xG/view?usp=drivesdk">https://drive.google.com/file/d/1Vb2yxmzRfhqiaPi5h7XxHEdgZPLJl9xG/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7833 25.06.2025 25.06.2025 Documentos solicitados