Arabidopsis PASTICCINO2 Is an Antiphosphatase Involved in Regulation of Cyclin-Dependent Kinase A W (Record no. 42207)
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| fixed length control field | 02087nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625124709.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-7894 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Arabidopsis PASTICCINO2 Is an Antiphosphatase Involved in Regulation of Cyclin-Dependent Kinase A W |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | The Plant Cell, 18, p.1426-1453, 2006 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | PASTICCINO2 (PAS2), a member of the protein Tyr phosphatase-like family, is conserved among all eukaryotes and is characterized by a mutated catalytic site. The cellular functions of the Tyr phosphatase-like proteins are still unknown, even if they are essential in yeast and mammals. Here, we demonstrate that PAS2 interacts with a cyclin-dependent kinase (CDK)that is phosphorylated on Tyr and not with its unphosphorylated isoform. Phosphorylation of the conserved regulatory Tyr-15 is involved in the binding of CDK to PAS2. Loss of the PAS2 function dephosphorylated Arabidopsis thaliana CDKA;1 and upregulated its kinase activity. In accordance with its role as a negative regulator of the cell cycle, overexpression of PAS2 slowed down cell division in suspension cell cultures at the G2-to-M transition and early mitosis and inhibited Arabidopsis seedling growth. The latter was accompanied by altered leaf development and accelerated cotyledon senescence. PAS2 was localized in the cytoplasm of dividing cells but moved into the nucleus upon cell differentiation, suggesting that the balance between cell division and differentiation is regulated through the interaction between CDKA;1 and the antiphosphatase PAS2. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Da Costa, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bach, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Landrieu, I. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bellec, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Catrice, O. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brown, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | De Veylder, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | De Veylder, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Inze D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Faurea, J.D. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1_WXLndI80EZsZuIKNc47S_FT9xhHZYMb/view?usp=drivesdk">https://drive.google.com/file/d/1_WXLndI80EZsZuIKNc47S_FT9xhHZYMb/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-7894 | 25.06.2025 | 25.06.2025 | Documentos solicitados |