Screening of traditionally used South African plants for antifungal activity against Candida albicans (Record no. 42235)

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control field MX-MdCICY
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control field 20250625124710.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7923
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245 10 - TITLE STATEMENT
Title Screening of traditionally used South African plants for antifungal activity against Candida albicans
490 0# - SERIES STATEMENT
Volume/sequential designation Journal of EthnoPharmacology, 86(2-3), p.235-241, 2003
520 3# - SUMMARY, ETC.
Summary, etc. Twenty-four South African medicinal plants were screened against Candida albicans standard strain ATCC 10231 and two clinical isolates from a 5-month-old baby and an adult, in an attempt to find a traditional remedy to treat oral candidiasis, which is prevalent in HIV-patients. Allium sativum L. and Tulbaghia violacea L. aqueous bulb extracts had MIC values of 0.56 and 3.25 mg/ml respectively, whilst Polygala myrtifolia L. leaves and Glycyrrhiza glabra L. rhizome extracts had MIC values of 1.56 mg/ml when tested against the 5-month-old isolate. Fresh water extracts stored at 4, 23 and 33 .C over a period of a week, were used to determine the stability of these extracts. Allium sativum and Tulbaghia violacea maintained activity at 4 .C, but not at higher temperatures, whereas Polygala myrtifolia and Glycyrrhiza glabra lost activity within a day even at 4 .C. The unpleasant taste of the two species with a garlic smell, could however not be masked, and as the smell following the eating of the two species would lead to HIV-patients being recognised, these two plants where not considered for further investigation. Therefore, Polygala myrtifolia and Glycyrrhiza glabra are being further investigated for use as an oral mouthwash in clinics and homes
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIFUNGAL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CANDIDA ALBICANS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HIV/AIDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRADITIONAL MEDICINE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Motsei, M.L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lindsey, K.L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name van Staden. J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jager, A.K.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1oTKsCBxK5ZatIZ6hBTNMcn2vTvmb32sG/view?usp=drivesdk">https://drive.google.com/file/d/1oTKsCBxK5ZatIZ6hBTNMcn2vTvmb32sG/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7923 25.06.2025 25.06.2025 Documentos solicitados