Early Steps in the Biosynthesis of NAD in Arabidopsis Start with Aspartate and Occur in the Plastid1 (Record no. 42265)

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control field 20250625124711.0
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7953
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Title Early Steps in the Biosynthesis of NAD in Arabidopsis Start with Aspartate and Occur in the Plastid1
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Volume/sequential designation Plant Physiology, 141, p.851-857, 2006
520 3# - SUMMARY, ETC.
Summary, etc. NADis a ubiquitous coenzyme involved in oxidation-reduction reactions and is synthesized by way of quinolinate. Animals and some bacteria synthesize quinolinate from tryptophan, whereas other bacteria synthesize quinolinate from aspartate (Asp)using L-Asp oxidase and quinolinate synthase. We show here that Arabidopsis (Arabidopsis thaliana)uses the Asp-to-quinolinate pathway. The Arabidopsis L-Asp oxidase or quinolinate synthase gene complemented the Escherichia coli mutant defective in the corresponding gene, and T-DNA-based disruption of either of these genes, as well as of the gene coding for the enzyme quinolinate phosphoribosyltransferase, was embryo lethal. An analysis of functional green fluorescent protein-fused constructs and in vitro assays of uptake into isolated chloroplasts demonstrated that these three enzymes are located in the plastid.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Katoh, A.
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Personal name Uenohara, K.
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Personal name Akita, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hashimoto, T.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1ZRFcb4kviNXuBeIM79Juo4VhZbKUyc96/view?usp=drivesdk">https://drive.google.com/file/d/1ZRFcb4kviNXuBeIM79Juo4VhZbKUyc96/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7953 25.06.2025 25.06.2025 Documentos solicitados