Phosphorylation and dephosphorylation events that regulate viral mRNA translation (Record no. 42298)

MARC details
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fixed length control field 01795nam a2200205Ia 4500
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control field MX-MdCICY
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control field 20250625124711.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-7986
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Title Phosphorylation and dephosphorylation events that regulate viral mRNA translation
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Volume/sequential designation Virus Research, 119(1), p.89-99, 2006
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Summary, etc. As they are completely dependent upon the protein synthesis machinery resident in the cells of their host to translate their mRNAs, it is imperative that viruses are able to effectively manipulate the elaborate cellular regulatory network that controls translation. Indeed, this exquisite dependence on host functions has made viral models attractive systems to explore translational regulatory mechanisms operative in eukaryotic cells. Central among these are an intricate array of phosphorylation and dephosphorylation events that have far reaching consequences on the activity of cellular translation factors. Not only do these modulate the activity of a given factor, but they can also determine if the translation of host proteins persists in infected cells, the efficiency with which viral mRNAs are translated and the outcome of a systemic host anti-viral response. In this review, we discuss how various viruses manipulate the phosphorylation state of key cellular translation factors, illustrating the critical nature these interactions play in virus replication, pathogenesis and innate host defense.
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Topical term or geographic name entry element TRANSLATIONAL CONTROL
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Topical term or geographic name entry element VIRUSES
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Topical term or geographic name entry element PHOSPHORYLATION
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Personal name Mohr, I.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1MCuyXaAwZAKXSSGA2fdYFCXnPEZEE_jw/view?usp=drivesdk">https://drive.google.com/file/d/1MCuyXaAwZAKXSSGA2fdYFCXnPEZEE_jw/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-7986 25.06.2025 25.06.2025 Documentos solicitados