MARC details
| 000 -LEADER |
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| fixed length control field |
02348nam a2200313Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625124715.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-8181 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Impact of fungal drug transporters on fungicide sensitivity, multidrug resistance and virulence |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Pest Management Science, 62(3), p.195-207, 2006 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Drug transporters are membrane proteins that provide protection for organisms against natural toxic products and fungicides. In plant pathogens, drug transporters function in baseline sensitivity to fungicides, multidrug resistance (MDR)and virulence on host plants. This paper describes drug transporters of the filamentous fungi Aspergillus nidulans (Eidam)Winter, Botrytis cinerea Pers and Mycosphaerella graminicola (F ¨ uckel)Schroter that function in fungicide sensitivity and resistance. The fungi possess ATP-binding cassette (ABC)drug transporters thatmediateMDRto fungicides in laboratory mutants. Similar mutants are not pronounced in field resistance to most classes of fungicide but may play a role in resistance to azoles. MDRmay also explain historical cases of resistance to aromatic hydrocarbon fungicides and dodine. In clinical situations, MDR development in Candida albicans (Robin)Berkhout mediated by ABC transporters in patients suffering from candidiasis is common after rolonged treatment with azoles. Factors that can explain this striking difference between agricultural and clinical situations are discussed. Attention is also paid to the risk of MDR development in plant pathogens in the future. Finally, the paper describes the impact of fungal drug transporters on drug discovery. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ABC TRANSPORTERS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ATP-BINDING CASSETTE TRANSPORTERS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FUNGICIDES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MULTIDRUG RESISTANCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ASPERGILLUS NIDULANS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BOTRYTIS CINEREA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MYCOSPHAERELLA GRAMINICOLA |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
de Waard, M.A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Andrade, A.C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hayashi, K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Schoonbeek, H.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Stergiopoulos, I. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zwiers, L.-H. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1f0d7HmY2MqFEdrxRYKodOwQQiw1kL36J/view?usp=drivesdk">https://drive.google.com/file/d/1f0d7HmY2MqFEdrxRYKodOwQQiw1kL36J/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
