Interplay between Arabidopsis Activating Factors E2Fb and E2Fa in Cell Cycle Progression and Development1[w] (Record no. 42652)

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control field MX-MdCICY
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control field 20250625124718.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-8348
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Title Interplay between Arabidopsis Activating Factors E2Fb and E2Fa in Cell Cycle Progression and Development1[w]
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Volume/sequential designation Plant Physiology, 140(4), p.1355-1366, 2006
520 3# - SUMMARY, ETC.
Summary, etc. Eukaryotic E2Fs are conserved transcription factors playing crucial and antagonistic roles in several pathways related to cell division, DNA repair, and differentiation. In plants, these processes are strictly intermingled at the growing zone to produce postembryonic development in response to internal signals and environmental cues. Of the six AtE2F proteins found in Arabidopsis (Arabidopsis thaliana), only AtE2Fa and AtE2Fb have been clearly indicated as activators of E2F-responsive genes. AtE2Fa activity was shown to induce S phase and endoreduplication, whereas the function of AtE2Fb and the interrelationship between these two transcription factors was unclear.We have investigated the role played by the AtE2Fb gene during cell cycle and development performing in situ RNA hybridization, immunolocalization of the AtE2Fb protein in planta, and analysis of AtE2Fb promoter activity in transgenic plants. Overexpression of AtE2Fb in transgenic Arabidopsis plants led to strikingodifications of themorphology of roots, cotyledons, and leaves that can be ascribed to stimulation of cell division. The accumulation of the AtE2Fb protein in these lines was paralleled by an increased expression of E2F-responsive G1/S and G2/M marker genes. These results suggest that AtE2Fa and AtE2Fb have specific expression patterns and play similar but distinct roles during cell cycle progression.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sozzani, R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Maggio, C.
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Personal name Varotto, S.
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Personal name Canova, S.
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Personal name Bergounioux, C.
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Personal name Albani, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cella, R.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1KLEmDRHDgdHBSeVoM77mMQnzGwYbo-sy/view?usp=drivesdk">https://drive.google.com/file/d/1KLEmDRHDgdHBSeVoM77mMQnzGwYbo-sy/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-8348 25.06.2025 25.06.2025 Documentos solicitados