MARC details
| 000 -LEADER |
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| fixed length control field |
02208nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625124718.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-8349 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Retinoblastoma protein regulates cell proliferation, differentiation, and endoreduplication in plants |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
The Plant Journal, 42(2), p.153-163, 2005 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Retinoblastoma protein (Rb)plays a key role in cell cycle control, cell differentiation, and apoptosis in animals. In this study, we used virus-induced gene silencing (VIGS)to investigate the cellular functions of Rb in higher plants. VIGS of NbRBR1, which encodes the Nicotiana benthamiana Rb homolog, resulted in growth retardation and abnormal organ development. At the cellular level, Rb suppression caused prolonged cell proliferation in tissues that are normally differentiated, which indicates that Rb is a negative regulator of plant cell division. Furthermore, differentiation of the epidermal pavement cells and trichomes was partially retarded, and stomatal clusters formed in the epidermis, likely due to uncontrolled cell division of stomata precursor cells. Rb suppression also caused extra DNA replication in endoreduplicating leaf cells, suggesting a role of Rb in the endocycle. These Rb phenotypes were accompanied by stimulated transcription of E2F and E2F-regulated S-phase genes. Thus, disruption of Rb function in plants leads to ectopic cell division in major organs that correlates with a delay in cell differentiation as well as increased endoreduplication, which indicates that Rb coordinates these processes in plant organ development. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
E2F |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ELEVATED CELL PROLIFERATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
S-PHASE GENES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
STOMATAL CLUSTERS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
VIRUS-INDUCED GENE SILENCING |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Park, J.A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ahn, J.W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kim, Y.K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kim, S.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kim, J.K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kim, W.T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Pai, H.S. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1CGGWiLS3YGpGHhPSYpIgKqhouAZXoPSU/view?usp=drivesdk">https://drive.google.com/file/d/1CGGWiLS3YGpGHhPSYpIgKqhouAZXoPSU/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
