Interactions of PIN and PGP auxin transport mechanisms (Record no. 42852)

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fixed length control field 02035nam a2200313Ia 4500
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control field MX-MdCICY
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control field 20250625124722.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-8548
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Title Interactions of PIN and PGP auxin transport mechanisms
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Volume/sequential designation Biochem. Soc. Trans. , 35(1), p.137-141, 2007
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Summary, etc. Polarized transport of the plant hormone auxin influences multiple growth processes in plants and is regulated by plasma-membrane-localized efflux and uptake carriers. The PGP (P-glycoprotein)ABC transporters (ATP-binding-cassette transporters), PIN (pin-formed)subfamily of major facilitator proteins and members of AUX/LAX families have been shown to independently transport auxin both in planta and in heterologous systems. However, PIN- and PGP-mediated transport in heterologous systems exhibits decreased substrate specificity and inhibitor-sensitivity compared with what is seen in plants and plant cells. To determine whether PIN-PGP interactions enhance transport specificity, we analysed interactions of the representative auxin-transporting PGPs with PIN1 and AUX1 in planta and in heterologous systems. Here, we provide evidence that PINs and PGPs interact and function both independently and co-ordinately to control polar auxin transport and impart transport specificity and directionality. These interactions take place in protein complexes stabilized by PGPs in detergent-resistant microdomains.
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Personal name Bandyopadhyay, A.
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Personal name Blakeslee, J.J.
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Personal name Lee, O.R.
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Personal name Mravec, J.
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Personal name Sauer, M.
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Personal name Titapiwatanakun, B.
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Personal name Makam, S.N.
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Personal name Makam, S.N.
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Personal name Geisler, M.
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Personal name Martinoia, E.
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Personal name Friml, J.
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Personal name Peer, W.A.
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Personal name Murphy, A.S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1U-Pu22ngtBVr9MCXN4i9TSrGNY7rWCrH/view?usp=drivesdk">https://drive.google.com/file/d/1U-Pu22ngtBVr9MCXN4i9TSrGNY7rWCrH/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-8548 25.06.2025 25.06.2025 Documentos solicitados