MARC details
| 000 -LEADER |
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| fixed length control field |
02479nam a2200313Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625124729.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-8907 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
RNA-directed DNA methylation mediated by DRD1 and Pol IVb: Aversatile pathway for transcriptional gene silencing in plants |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Biochimica et Biophysica Acta, 1796(5-6), p.358-374, 2007 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
RNA-directed DNA methylation, which is one of several RNAi-mediated pathways in the nucleus, has been highly elaborated in the plant kingdom. RNA-directed DNA methylation requires for the most part conventional DNA methyltransferases, histone modifying enzymes and RNAi proteins; however, several novel, plant-specific proteins that are essential for this process have been identified recently. DRD1 (defective in RNA-directed DNA methylation)is a putative SWI2/SNF2-like chromatin remodelling protein; DRD2 and DRD3 (renamed NRPD2a and NRPD1b, respectively)are subunits of Pol IVb, a putative RNA polymerase found only in plants. Interestingly, DRD1 and Pol IVb appear to be required not only for RNA-directed de novo methylation, but also for full erasure of methylation when the RNA trigger is withdrawn. These proteins thus have the potential to facilitate dynamic regulation of DNA methylation. Prominent targets of RNA-directed DNA methylation in the Arabidopsis thaliana genome include retrotransposon long terminal repeats (LTRs), which have bidirectional promoter/enhancer activities, and other types of intergenic transposons and repeats. Intergenic solitary LTRs that are targeted for reversible methylation by the DRD1/Pol IVb pathway can potentially act as switches or rheostats for neighboring plant genes. The resulting alterations in gene expression patterns may promote physiological flexibility and adaptation to the environment. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
DNA DEMETHYLATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
HETEROCHROMATIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
POL IV |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
RNA-DIRECTED DNA METHYLATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
RNAI |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
TRANSCRIPTIONAL GENE SILENCING |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Huettel, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kanno, T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Daxinger, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Bucher, E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Van Der Winden, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Matzke, A.J.M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Matzke, M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1wpqjQNkJDOC8icefQJ1npTZpWKESADEN/view?usp=drivesdk">https://drive.google.com/file/d/1wpqjQNkJDOC8icefQJ1npTZpWKESADEN/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
