Signals from Chloroplasts Converge to Regulate Nuclear Gene Expression (Record no. 43193)

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control field MX-MdCICY
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control field 20250625124729.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-8931
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Title Signals from Chloroplasts Converge to Regulate Nuclear Gene Expression
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Volume/sequential designation Science, 316, p.715-719, 2007
520 3# - SUMMARY, ETC.
Summary, etc. Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with chloroplast function and is essential for the photoautotrophic life-style of plants. Three retrograde signals have been described, but little is known of their signaling pathways. We show here that GUN1, a chloroplast-localized pentatricopeptide-repeat protein, and ABI4, an Apetala 2 (AP2)-type transcription factor, are common to all three pathways. ABI4 binds the promoter of a retrograde-regulated gene through a conserved motif found in close proximity to a light-regulatory element. We propose a model in which multiple indicators of aberrant plastid function in Arabidopsis are integrated upstream of GUN1 within plastids, which leads to ABI4- mediated repression of nuclear-encoded genes.
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Personal name Koussevitzky, S.
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Personal name Nott, A.
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Personal name Mockler, T.C.
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Personal name Hong, F.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/14R7H3nDblW-omADLkrAUdl6Xw34QFrep/view?usp=drivesdk">https://drive.google.com/file/d/14R7H3nDblW-omADLkrAUdl6Xw34QFrep/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-8931 25.06.2025 25.06.2025 Documentos solicitados