MARC details
| 000 -LEADER |
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| fixed length control field |
02147nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625124729.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-8935 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
MgMfs1, a major facilitator superfamily transporter from the fungal wheat pathogen Mycosphaerella graminicola, is a strong protectant against natural toxic compounds and fungicides |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Fungal Genetics and Biology, 44(5), p.378-388, 2007 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
MgMfs1, a major facilitator superfamily (MFS)gene from the wheat pathogenic fungus Mycosphaerella graminicola, was identiWed in expressed sequence tag (EST)libraries. The encoded protein has high homology to members of the drug:H+ antiporter eZux family of MFS transporters with 14 predicted transmembrane spanners (DHA14), implicated in mycotoxin secretion and multidrug resistance. Heterologous expression of MgMfs1 in a hypersensitive Saccharomyces cerevisiae strain resulted in a strong decrease in sensitivity of this organism to a broad range of unrelated synthetic and natural toxic compounds. The sensitivity of MgMfs1 disruption mutants of M. graminicola to most of these compounds was similar when compared to the wild-type but the sensitivity to strobilurin fungicides and the mycotoxin cercosporin was increased. Virulence of the disruption mutants on wheat seedlings was not aVected. The results indicate that MgMfs1 is a true multidrug transporter that can function as a determinant of pathogen sensitivity and resistance to fungal toxins and fungicides. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MFS TRANSPORTER |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MYCOSPHAERELLA GRAMINICOLA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
MULTIDRUG RESISTANCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FUNGICIDE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
STROBILURIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CERCOSPORIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SEPTORIA TRITICI LEAF BLOTCH |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SACCHAROMYCES CEREVISIAE |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Roohparvar, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
De Waard, M.A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kema, G.H.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Zwiers, L.H. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1STDllH8GN6iaDoWkQ3azAOjsxgnPTEmK/view?usp=drivesdk">https://drive.google.com/file/d/1STDllH8GN6iaDoWkQ3azAOjsxgnPTEmK/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
