Generalization of Courtship Learning in Drosophila Is Mediated by cis-Vaccenyl Acetate (Record no. 43274)

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fixed length control field 02190nam a2200253Ia 4500
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625124731.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-9014
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245 10 - TITLE STATEMENT
Title Generalization of Courtship Learning in Drosophila Is Mediated by cis-Vaccenyl Acetate
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Volume/sequential designation Current Biology, 17(7), p.599-605, 2007
520 3# - SUMMARY, ETC.
Summary, etc. Reproductive behavior in Drosophila has both stereotyped and plastic components that are driven by ageand sex-specific chemical cues. Males who unsuccessfully court virgin females subsequently avoid females that are of the same age as the trainer. In contrast, males trained with mature mated females associate volatile appetitive and aversive pheromonal cues and learn to suppress courtship of all females. Here we show that the volatile aversive pheromone that leads to generalized learning with mated females is (Z)-11-octadecenyl acetate (cis-vaccenyl acetate, cVA). cVA is a major component of the male cuticular hydrocarbon profile, but it is not found on virgin females. During copulation, cVA is transferred to the female in ejaculate along with sperm and peptides that decrease her sexual receptivity. When males sense cVA (either synthetic or from mated female or male extracts)in the context of female pheromone, they develop a generalized suppression of courtship. The effects of cVA on initial courtship of virgin females can be blocked by expression of tetanus toxin in Or65a, but not Or67d neurons, demonstrating that the aversive effects of this pheromone are mediated by a specific class of olfactory neuron. These findings suggest that transfer of cVA to females during mating may be part of the male's strategy to suppress reproduction by competing males.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ejima, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Smith, B.P.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lucas, C.
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Personal name van der Goes van Naters, W.
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Personal name Miller, C.J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Carlson, J.R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Levine, J.D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Levine, J.D.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1gRwYzHxtRVFoP-YVZ-2N1bu5D1RyEbNm/view?usp=drivesdk">https://drive.google.com/file/d/1gRwYzHxtRVFoP-YVZ-2N1bu5D1RyEbNm/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-9014 25.06.2025 25.06.2025 Documentos solicitados