Synthesis of Plumbagin Derivatives and their Inhibitory Activities against Ehrlich Ascites Carcinoma in vivo and Leishmania donovani Promastigotes in vitro (Record no. 43913)
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| fixed length control field | 01785nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140617.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-9667 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Synthesis of Plumbagin Derivatives and their Inhibitory Activities against Ehrlich Ascites Carcinoma in vivo and Leishmania donovani Promastigotes in vitro |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Phytotherapy Research, 16(2), p.133-137, 2002 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Plumbagin, a plant-derived bioactive naphthoquinonoid compound, was converted to a hydroquinonoid derivative, which was studied for its tumour-inhibitory and antileishmanial activities for the first time. A similar chemical transformation was undertaken on an analogous dimeric compound, diospyrin, and its bioassay results were compared with those of the plumbagin derivative. Synthesis of the derivative of plumbagin did not result in a marked enhancement of the tumour-inhibitory activity, whereas the improvement was obvious in the case of diospyrin vis a` vis its hydroquinonoid analogue. The conversion of diospyrin to the hydroquinonoid compound also led to a substantial increase in the antileishmanial activity, while a similar conversion of plumbagin failed to do so. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PLUMBAGIN DERIVATIVE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DIOSPYRIN DERIVATIVE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | NAPHTHOQUINONE DERIVATIVE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | EHRLICH ASCITES CARCINOMA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | LEISHMANIA DONOVANI |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hazra, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sarkar, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bhattacharyya, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ghosh, P.K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chel, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dinda, B. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1XWZK2fwTpihtp12f-7luGWwqDAODguGD/view?usp=drivesdk">https://drive.google.com/file/d/1XWZK2fwTpihtp12f-7luGWwqDAODguGD/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-9667 | 25.06.2025 | 25.06.2025 | Documentos solicitados |