Synthesis, Characterization and Cytocompatibility of Polyurethaneurea Elastomers with Designed Elastase Sensitivity (Record no. 44055)

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control field MX-MdCICY
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control field 20250625140619.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-9809
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245 10 - TITLE STATEMENT
Title Synthesis, Characterization and Cytocompatibility of Polyurethaneurea Elastomers with Designed Elastase Sensitivity
490 0# - SERIES STATEMENT
Volume/sequential designation BioMacromolecules, 6(5), p.2833-2842, 2005
520 3# - SUMMARY, ETC.
Summary, etc. In designing a synthetic scaffold for engineering soft, mechanically active tissues, desirable properties include elasticity, support of cell adhesion and growth, ease of processability, and responsiveness to in vivo remodeling. To achieve these properties, we have developed a family of thermoplastic elastomers, polyurethaneureas (PUs), that possess enzymatic remodeling capabilities in addition to simple hydrolytic lability. PUs were synthesized using either polycaprolactone or triblock copolymer polycaprolactone-bpoly( ethylene glycol)-b-polycaprolactone as the soft segment, 1,4-butanediisocyanate as the hard segment, and the peptide Ala-Ala-Lys as a chain extender. The synthesized PUs had high molecular weights, low glass transition temperatures (<-54 °C), and were flexible with breaking strains of 670-890
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Guan, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wagner, W.R.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1TRqvOac8tOITcdcVY4zB1MkaBj9NTuQG/view?usp=drivesdk">https://drive.google.com/file/d/1TRqvOac8tOITcdcVY4zB1MkaBj9NTuQG/view?usp=drivesdk</a>
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-9809 25.06.2025 25.06.2025 Documentos solicitados