Multiple Actin-Related Proteins of Saccharomyces cerevisiae Are Present in the Nucleus1 (Record no. 44133)

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fixed length control field 02186nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140621.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-9888
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Title Multiple Actin-Related Proteins of Saccharomyces cerevisiae Are Present in the Nucleus1
490 0# - SERIES STATEMENT
Volume/sequential designation J. Biochem., 128(4), p.665-671, 2000
520 3# - SUMMARY, ETC.
Summary, etc. An increasing number of actin-related proteins (Arps), which share the basal structure with skeletal actin but possess distinct functions, have been found in a wide variety of organisms. Individual Arps of Saccharomyces cerevisiae were classified into Arps 1-10 based on the relatedness of their sequences and functions, where Arpl is the most similar to actin, and ArplO is the least similar. While Arps 1-3 and their orthologs in other organisms are localized exclusively in the cytoplasm, Arp4 (also known as Act3)is localized in the nucleus and is involved in transcriptional regulation. Here we examined the more divergent Arps for possible nuclear functions. We show that Arps 5-8 are localized in the nucleus, but ArplO is not. The nuclear export signals identified in actin are well conserved in the cytoplasmic Arps, Arps 1-3, but less conserved in the nuclear Arps. Gel filtration chromatography experiments show that the nuclear Arps are larger than monomer in size and thus are present in multi-protein complexes. Since nuclear protein complexes containing Arps are found to be responsible for histone acetylation and chromatin remodeling, it is suggested that most of the divergent Arps are involved in the transcriptional regulation through chromatin modulation.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ACTIN-RELATED PROTEIN
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Topical term or geographic name entry element CHROMATIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NUCLEAR LOCALIZATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PROTEIN COMPLEX
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRANSCRIPTIONAL REGULATION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Harata, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Oma, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tabuchi, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Stillman, D.J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mizuno, S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Wz5je_k_06P_nyBoxeketn1KwL59Fh0M/view?usp=drivesdk">https://drive.google.com/file/d/1Wz5je_k_06P_nyBoxeketn1KwL59Fh0M/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-9888 25.06.2025 25.06.2025 Documentos solicitados