Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors (Record no. 44140)

MARC details
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control field MX-MdCICY
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control field 20250625140621.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-9895
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245 10 - TITLE STATEMENT
Title Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors
490 0# - SERIES STATEMENT
Volume/sequential designation Plant Biotechnology Journal, 6(2), p.160-175, 2008
520 3# - SUMMARY, ETC.
Summary, etc. Genes encoding regulatory factors isolated from Arabidopsis , soybean and corn have been screened to identify those that modulate the expression of genes encoding for enzymes involved in the biosynthesis of morphinan alkaloids in opium poppy ( Papaver somniferum ) and benzophenanthridine alkaloids in California poppy ( Eschscholzia californica ). In opium poppy, the over-expression of selected regulatory factors increased the levels of PsCOR (codeinone reductase), Ps4 _O OMT ( S -adenosyl- L -methionine:3 _O -hydroxy- N -methylcoclaurine 4_O O ltransferase)and Ps6OMT [( R , S )-norcoclaurine 6- O -methyltransferase]transcripts by 10- to more than 100-fold. These transcriptional activations translated into an enhancement of alkaloid production in opium poppy of up to at least 10-fold. In California poppy, the transactivation effect of regulatory factor WRKY1 resulted in an increase of up to 60-fold in the level of EcCYP80B1 [( S )- N -methylcoclaurine 3 _O -hydroxylase]and EcBBE (berberine bridge enzyme)transcripts. As a result, the accumulations of selected alkaloid intermediates were enhanced up to 30-fold. The transactivation effects of other regulatory factors led to the accumulation of the same intermediates. These regulatory factors also led to the production of new alkaloids in California poppy callus culture.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CALIFORNIA POPPY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MORPHINAN ALKALOIDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MORPHINE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element OPIUM POPPY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element THEBAINE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRANSCRIPTION FACTORS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Apuya, N.R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Park, J.H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ahyow, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Davidow, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Van Fleet, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rarang, J.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rarang, J.C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Johnson, T.J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yoo, H.D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Trieu, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Krueger, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wu, C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lu, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Flavell, R.B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Bobzin, S.C.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Z845koqDcGu4xba3yU8hSz7l9zqQPYQk/view?usp=drivesdk">https://drive.google.com/file/d/1Z845koqDcGu4xba3yU8hSz7l9zqQPYQk/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-9895 25.06.2025 25.06.2025 Documentos solicitados