Studies on the traditional herbal anthelmintic Chenopodium ambrosioides L.: ethnopharmacological evaluation and clinical field trials (Record no. 44154)
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| fixed length control field | 03249nam a2200169Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140621.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-9911 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Studies on the traditional herbal anthelmintic Chenopodium ambrosioides L.: ethnopharmacological evaluation and clinical field trials |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Sm. Sci. Med., 21(8), p.879-886, 1985 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | infusions and decoctions of the leaves. roots and inflorescences of the herbaceous shrub Cl~rnoporliutn omhrosioide.7 (American wormseed, goosefoot. epazofr, @co)and related species indigenous to the New World have been used for centuries as dietary condiments and as traditional anthelmintics by native peoples for the treatment of intestinal worms. Commercial preparations of oil of chenopodium and its active constituent. ascaridol, obtained by steam distillation. have been and continue to be. used with considerable success in mass treatment campaigns. Ethnopharmacological studies in a community of Mayan subsistence farmers in Chiapas. Mexico, confirmed that decoctions containing up to 300 mg of dry plant material per kg body weight (MGKGW)were widely used and traditionally highly regarded in the treatment of ascariasis. However, therapeutic doses of up to 6000 MGKGW of powdered, dried plant had no significant anthelmintic effect on the adults of Necator. Trichuris of Ascaris. Gas-liquid chromatographic analyses of plant samples used consistently demonstrated the presence of ascaridol in the expected amounts. Possible origins of subjective belief in the efficacy of C. amhrosioides as used. may be related to the positive association of spontaneous, or peristalsis-induced passage of senescent worms immediately following a therapeutic episode. It is also possible that in the past varieties of the plant containing much more ascaridol were used. The results of these controlled field studies did not sustain widely held traditional beliefs. nor the value of therapeutic practices regarding this plant. It is, therefore. essential that all indigenous ethnomedical practices be objectively evaluated for efficacy and safety using appropriate protocols before being considered for adoptation or promotion in health care programs. Although this herbal drug was not efficacious as currently used, its essential oil, which is highly effective. could be extracted using technology and materials available at the village level. The plant already is known. accepted. and widely grown by rural peoples. Intestinal helminths are a constant and serious health problem in most such communities. Commercially available pharmaceuticals are effective but too expenwe for periodic treatment and prophylaxis. Reinfection immediately following treatment is inevitable given the socioeconomic, climatic and hygienic conditions in such communities. The local production and application of an effective and inexpensive anthelmintic. therefore, would be of considerable public health and economic importance. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kliks, M.M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1Ru_x7ZDJbu2yK-rdO4HbHhXUJQVWvEgX/view?usp=drivesdk">https://drive.google.com/file/d/1Ru_x7ZDJbu2yK-rdO4HbHhXUJQVWvEgX/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-9911 | 25.06.2025 | 25.06.2025 | Documentos solicitados |