Validate antibacterial mode and find main bioactive components of traditional Chinese medicine Aquilegia oxysepala (Record no. 44155)
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| 000 -LEADER | |
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| fixed length control field | 01663nam a2200193Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140621.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-9912 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Validate antibacterial mode and find main bioactive components of traditional Chinese medicine Aquilegia oxysepala |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Bioorganic & Medicinal Chemistry Letters, 17(7), p.1855-1859, 2007 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Traditional Chinese medicines have been used for thousands of years and are still being used as one of the regular treatments for many diseases. However, their mechanisms were still unknown. In this investigation, a possible procedure combining metabonomics and principal component analysis to investigate antibacterial modes of action and find main antimicrobial component in traditional Chinese medicine, Aquilegia oxysepala, is developed. Metabolic profiles of Staphylococcus aureus treated with nine antibiotics of known modes of action and with A. oxysepala were acquired by HPLC/DAD/ESI-MS. After statistical processing by principal components analysis on metabolic profiles, two conclusions could be drawn: (1)the target of A. oxysepala may be similar to that of lincolmensin, erythromycin, chloromycetin, streptomycin, and acheomycin, whose targets are protein; (2)its bioactive component playing main antimicrobial roles on S. aureus may be maguoflorine. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yu, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yi, Z. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liang, Y. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1Rl8v8rj09vFKMD_5NsBCb4N1SCvFEL7q/view?usp=drivesdk">https://drive.google.com/file/d/1Rl8v8rj09vFKMD_5NsBCb4N1SCvFEL7q/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-9912 | 25.06.2025 | 25.06.2025 | Documentos solicitados |