In silicio Identification of Glycosyl-Phosphatidylinositol-Anchored Plasma-Membrane and Cell Wall Proteins of Saccharomyces cerevisiae (Record no. 44296)
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| fixed length control field | 02332nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140624.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-10054 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | In silicio Identification of Glycosyl-Phosphatidylinositol-Anchored Plasma-Membrane and Cell Wall Proteins of Saccharomyces cerevisiae |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Yeast, 13(15), p.1477-1489, 1998 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Use of the Von Heijne algorithm allowed the identification of 686 open reading frames (ORFs)in the genome of Saccharomyces cerevisiae that encode proteins with a potential N-terminal signal sequence for entering the secretory pathway. On further analysis, 51 of these proteins contain a potential glycosyl-phosphatidylinositol (GPI)- attachment signal. Seven additional ORFs were found to belong to this group. Upon examination of the possible GPI-attachment sites, it was found that in yeast the most probable amino acids for GPI-attachment are asparagine and glycine. In yeast, GPI-proteins are found at the cell surface, either attached to the plasma-membrane or as an intrinsic part of the cell wall. It was noted that plasma-membrane GPI-proteins possess a dibasic residue motif just before their predicted GPI-attachment site. Based on this, and on homologies between proteins, families of plasma-membrane and cell wall proteins were assigned, revealing 20 potential plasma-membrane and 38 potential cell wall proteins. For members of three plasma-membrane protein families, a function has been described. On the other hand, most of the cell wall proteins seem to be structural components of the wall, responsive to different growth conditions. The GPI-attachment site of yeast slightly differs from mammalian cells. This might be of use in the development of anti-fungal drugs. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GPI-ANCHOR |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GPI-ATTACHMENT SITE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | YEAST |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ASCOMYCETES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | FUNGI |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heleen, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Caro, P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tettelin, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vossen, J.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ram, A.F.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Van Den Ende, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Klis, F.M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1bN_kIqGQD5IKExYa7C1iSOxMAvg7W4UN/view?usp=drivesdk">https://drive.google.com/file/d/1bN_kIqGQD5IKExYa7C1iSOxMAvg7W4UN/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-10054 | 25.06.2025 | 25.06.2025 | Documentos solicitados |