Construction of Skeletal Myoblast-Based Polyurethane Scaffolds for Myocardial Repair (Record no. 44396)

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fixed length control field 02022nam a2200301Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625140626.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-10157
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245 10 - TITLE STATEMENT
Title Construction of Skeletal Myoblast-Based Polyurethane Scaffolds for Myocardial Repair
490 0# - SERIES STATEMENT
Volume/sequential designation Artificial Organ, 31(6), p.425-433, 2007
520 3# - SUMMARY, ETC.
Summary, etc. Intramyocardial transplantation of skeletal myoblasts augments postinfarction cardiac function. However, poor survival of injected cells limits this therapy. It is hypothesized that implantation of myoblast-based scaffolds would result in greater cell survival. Rat skeletal myoblasts were seeded on highly porous polyurethane (PU)scaffolds (7.5 ¥ 7.5 ¥ 2.0 mm).The effect of several scaffold pretreatments, initial cell densities, and culture periods was tested by DNA-based cell count and viability assessment. Seeded PU scaffolds were implanted on infarcted hearts and immunohistology was performed 4 weeks later. Precoating with laminin allowed the most favorable cell attachment. An initial inoculation with 5 ¥ 106 cells followed by a 15-day culture period resulted in optimal myoblast proliferation. Four weeks after their implantation in rats, numerous myoblasts were found throughout the seeded patches although no sign of differentiation could be observed. This myoblast seeding technique on PU allows transfer of a large number of living myoblasts to a damaged myocardium.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MYOBLAST
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CELL TRANSPLANTATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TISSUE ENGINEERING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SCAFFOLD
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MYOCARDIAL INFARCTION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Siepe, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Giraud, M.N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Liljensten, E.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Nydegger, U.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Menasche, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Carrel, T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tevaearai, H.T.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1HvHmLAGFg-CqnauFUiM8JQgbw5-YT0b3/view?usp=drivesdk">https://drive.google.com/file/d/1HvHmLAGFg-CqnauFUiM8JQgbw5-YT0b3/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-10157 25.06.2025 25.06.2025 Documentos solicitados