Proteomics and regulomics: the yin and yang of functional genomics (Record no. 44712)

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control field MX-MdCICY
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control field 20250625140632.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-10480
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Title Proteomics and regulomics: the yin and yang of functional genomics
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Volume/sequential designation Mass Spectrometry Reviews, 23(1), p.25-33, 2003
520 3# - SUMMARY, ETC.
Summary, etc. Protein analysis is a field of research with a long history. Recently, the development of a series of proteomics approaches, i.e., simultaneous analyses on all or a majority of proteins in a cell at a given state, has reinvigorated protein analyses. Mass Spectrometry also developed into one of the most versatile technical tools supporting or even enabling many proteomicsoriented approaches, providing a convenient link between experimental protein analysis and the corresponding amino acid sequences. Thus direct links to the genomic sequence can be established, which opens the door for a synergistic combination with genomic sequence analysis. This review focuses especially on aspects of genome-wide transcription control, regulomics in analogy to all the other -omics, and how a combination of MS-based proteomics with in silico regulomics analyses can produce synergistic effects in the quest to understand how cells function. This is illustrated on a real life example showing how the MS-analysis and in silico promoter analysis can extend the list of candidates for signaling pathways, here the MAP kinase pathway
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PROTEOMICS
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Topical term or geographic name entry element REGULAMICS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element FUNCTIONAL GENOMICS
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Personal name Werner, T.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1UIy-N3WgyQDFZOoof5qtTQdgyDENjhlQ/view?usp=drivesdk">https://drive.google.com/file/d/1UIy-N3WgyQDFZOoof5qtTQdgyDENjhlQ/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-10480 25.06.2025 25.06.2025 Documentos solicitados