Arresting developments in heptahelical receptor signaling and regulation (Record no. 44933)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01297nam a2200181Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625140636.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-10701 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Arresting developments in heptahelical receptor signaling and regulation |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Trends in Cell Biology, 12, p.130-138, 2002 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | It is well established that the function of most heptahelical receptors (seven-transmembrane-span receptors; 7TMRs)is tightly regulated by the desensitizing actions of arrestins. Desensitization is the waning of 7TMR-mediated signals after prolonged exposure to agonist and occurs when arrestins bind to agonist-occupied and phosphorylated receptors, uncoupling the receptors from G proteins and preventing further signaling. Recently, there has been a marked shift in the focus of research into arrestin function because it has become clear that they not only prevent signaling from 7TMRs but also initiate and direct new signals from the very 7TMRs that they desensitize. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Perry, S.J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lefkowitz, R.L. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1QHiux04PuzCe-5ha0EKbiIt5-pOYK9nh/view?usp=drivesdk">https://drive.google.com/file/d/1QHiux04PuzCe-5ha0EKbiIt5-pOYK9nh/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-10701 | 25.06.2025 | 25.06.2025 | Documentos solicitados |
